Cell cycle deregulation and mosaic loss of Ext1 drive peripheral chondrosarcomagenesis in the mouse and reveal an intrinsic cilia deficiency.

de Andrea, Carlos E; Zhu, Ju-Fen; Jin, Huifeng; Bovée, Judith V M G; Jones, Kevin B

de Andrea, Carlos E; Zhu, Ju-Fen; Jin, Huifeng; Bovée, Judith V M G; Jones, Kevin B.

Affiliation

de Andrea CE; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Zhu JF; Department of Histology and Pathology, University of Navarra, Pamplona, Spain.
Jin H; Department of Orthopaedics, University of Utah, Salt Lake City, Utah, USA.
Bovée JV; Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Jones KB; Department of Orthopaedics, University of Utah, Salt Lake City, Utah, USA.

J Pathol ; 236(2): 210-8, 2015 Jun.

Article de En | MEDLINE | ID: mdl-25644707

Sujet(s)
Mots clés

chondrosarcoma; mouse genetic model; osteochondroma; primary cilium; tumour suppressor

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs osseuses / Ostéochondrome / Chondrosarcome / N-acetylglucosaminyltransferase Limites: Animals Langue: En Journal: J Pathol Année: 2015 Type de document: Article Pays d'affiliation: Pays-Bas Pays de publication: Royaume-Uni

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