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Crystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egress.
Kim, Jeong Joo; Flueck, Christian; Franz, Eugen; Sanabria-Figueroa, Eduardo; Thompson, Eloise; Lorenz, Robin; Bertinetti, Daniela; Baker, David A; Herberg, Friedrich W; Kim, Choel.
Affiliation
  • Kim JJ; Department of Pharmacology, Baylor College of Medicine, Houston, Texas, United States of America; Department of Biochemistry, University of Kassel, Kassel, Hesse, Germany.
  • Flueck C; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
  • Franz E; Department of Biochemistry, University of Kassel, Kassel, Hesse, Germany.
  • Sanabria-Figueroa E; Department of Pharmacology, Baylor College of Medicine, Houston, Texas, United States of America.
  • Thompson E; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
  • Lorenz R; Department of Biochemistry, University of Kassel, Kassel, Hesse, Germany.
  • Bertinetti D; Department of Biochemistry, University of Kassel, Kassel, Hesse, Germany.
  • Baker DA; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
  • Herberg FW; Department of Biochemistry, University of Kassel, Kassel, Hesse, Germany.
  • Kim C; Department of Pharmacology, Baylor College of Medicine, Houston, Texas, United States of America; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America.
PLoS Pathog ; 11(2): e1004639, 2015 Feb.
Article de En | MEDLINE | ID: mdl-25646845

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Plasmodium falciparum / Protéines de protozoaire / Cyclic GMP-Dependent Protein Kinases / Mérozoïtes / Étapes du cycle de vie Langue: En Journal: PLoS Pathog Année: 2015 Type de document: Article Pays d'affiliation: Allemagne

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Plasmodium falciparum / Protéines de protozoaire / Cyclic GMP-Dependent Protein Kinases / Mérozoïtes / Étapes du cycle de vie Langue: En Journal: PLoS Pathog Année: 2015 Type de document: Article Pays d'affiliation: Allemagne