Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: novel anti-tumor mechanisms of Cannabidiol in breast cancer.

Elbaz, Mohamad; Nasser, Mohd W; Ravi, Janani; Wani, Nissar A; Ahirwar, Dinesh K; Zhao, Helong; Oghumu, Steve; Satoskar, Abhay R; Shilo, Konstantin; Carson, William E; Ganju, Ramesh K

Elbaz, Mohamad; Nasser, Mohd W; Ravi, Janani; Wani, Nissar A; Ahirwar, Dinesh K; Zhao, Helong; Oghumu, Steve; Satoskar, Abhay R; Shilo, Konstantin; Carson, William E; Ganju, Ramesh K.

Affiliation

Elbaz M; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: elbaz.2@osu.edu.
Nasser MW; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: Mohd.Nasser@osumc.edu.
Ravi J; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: Janani.Ravi@osumc.edu.
Wani NA; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: Nissar.Wani@osumc.edu.
Ahirwar DK; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: Dinesh.Ahirwar@osumc.edu.
Zhao H; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: Helong.Zhao@osumc.edu.
Oghumu S; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: Steve.Oghumu@osumc.edu.
Satoskar AR; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: abhay.satoskar@osumc.edu.
Shilo K; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: Konstantin.Shilo@osumc.edu.
Carson WE; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA; Department of Surgery, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: carson.77@osu.edu.
Ganju RK; Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address: Ramesh.ganju@osumc.edu.

Mol Oncol ; 9(4): 906-19, 2015 Apr.

Article de En | MEDLINE | ID: mdl-25660577

Sujet(s)
Mots clés

Cannabidiol; EGFR; Triple negative breast cancer; Tumor microenvironment

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du sein / Cannabidiol / Facteur de croissance épidermique / Microenvironnement tumoral / Récepteurs ErbB / Antinéoplasiques Type d'étude: Prognostic_studies Limites: Animals / Female / Humans Langue: En Journal: Mol Oncol Sujet du journal: BIOLOGIA MOLECULAR / NEOPLASIAS Année: 2015 Type de document: Article

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