Metadoxine Versus Placebo for the Treatment of Non-alcoholic Steatohepatitis: A Randomized Controlled Trial.

Shenoy, Kotacherry T; Balakumaran, Leena K; Mathew, Philip; Prasad, Mohan; Prabhakar, Boddu; Sood, Ajit; Singh, Shivaram P; Rao, Nagaraj P; Zargar, Shoukat A; Bignamini, Angelo A

Shenoy, Kotacherry T; Balakumaran, Leena K; Mathew, Philip; Prasad, Mohan; Prabhakar, Boddu; Sood, Ajit; Singh, Shivaram P; Rao, Nagaraj P; Zargar, Shoukat A; Bignamini, Angelo A.

Affiliation

Shenoy KT; Sree Gokulam Medical College and Research Foundation, Trivandrum, India ; Population Health and Research Institute, Trivandrum, India.
Balakumaran LK; Population Health and Research Institute, Trivandrum, India.
Mathew P; PVS Memorial Hospital, Cochin, India.
Prasad M; G. Hospital & Post Graduate Institute, Coimbatore, India.
Prabhakar B; Osmania Medical College & Hospital, Hyderabad, India.
Sood A; Dayanand Medical College & Hospital, Ludhiana, India.
Singh SP; S.C.B. Medical College, Cuttack, India.
Rao NP; Asian Institute of Gastroenterology, Hyderabad, India.
Zargar SA; Sher-I-Kashmir Institute of Medical Sciences, Kashmir, India.
Bignamini AA; School of Specialization in Hospital Pharmacy, University of Milan, Italy.

J Clin Exp Hepatol ; 4(2): 94-100, 2014 Jun.

Article de En | MEDLINE | ID: mdl-25755546

Mots clés

ALD, alcoholic liver disease; ALT, alanine transaminase; ANCOVA, analysis of covariance; AST, aspartate transaminase; ATP, adenosine triphosphate; GGT, gamma-glutamyl transferase; GSH, glutathione; HOMA-IR, homeostasis model assessment for insulin resistance; ITT, intention to treat; MRI, magnetic resonance imaging; MRS, MR spectroscopy; NADH, nicotinamide adenine dinucleotide; NAFLD, non-alcoholic fatty liver disease; NASH; NASH, non-alcoholic steatohepatitis; PDFF, proton-density fat-fraction; RCTs, randomized clinical trials; RIQ, range interquartile; TNF, tumor necrosis factors; controlled clinical trial; metadoxine

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Type d'étude: Clinical_trials / Prognostic_studies Langue: En Journal: J Clin Exp Hepatol Année: 2014 Type de document: Article Pays d'affiliation: Inde

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