Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis.

Tang, Yanjuan; Halvarsson, Camilla; Nordigården, Amanda; Kumar, Komal; Åhsberg, Josefine; Rörby, Emma; Wong, Wan Man; Jönsson, Jan-Ingvar

Tang, Yanjuan; Halvarsson, Camilla; Nordigården, Amanda; Kumar, Komal; Åhsberg, Josefine; Rörby, Emma; Wong, Wan Man; Jönsson, Jan-Ingvar.

Affiliation

Tang Y; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Halvarsson C; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden; Linköping Integrative Regenerative Medicine Centre, Linköping University, Linköping, Sweden.
Nordigården A; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Kumar K; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Åhsberg J; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Rörby E; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Wong WM; Lund Strategic Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.
Jönsson JI; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden; Linköping Integrative Regenerative Medicine Centre, Linköping University, Linköping, Sweden. Electronic address: jan-ingvar.jonsson@liu.se.

Exp Hematol ; 43(7): 554-64, 2015 Jul.

Article de En | MEDLINE | ID: mdl-25931014

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cellules souches hématopoïétiques / Leucémie aigüe myéloïde / Apoptose / Protéines proto-oncogènes c-akt / Protéines tumorales Limites: Animals Langue: En Journal: Exp Hematol Année: 2015 Type de document: Article Pays d'affiliation: Suède Pays de publication: Pays-Bas

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