Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.

Jaako, P; Debnath, S; Olsson, K; Zhang, Y; Flygare, J; Lindström, M S; Bryder, D; Karlsson, S

Jaako, P; Debnath, S; Olsson, K; Zhang, Y; Flygare, J; Lindström, M S; Bryder, D; Karlsson, S.

Affiliation

Jaako P; Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund, Sweden.
Debnath S; Molecular Hematology, Lund Stem Cell Center, Lund University, Lund, Sweden.
Olsson K; Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund, Sweden.
Zhang Y; Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund, Sweden.
Flygare J; Department of Radiation Oncology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Lindström MS; Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund, Sweden.
Bryder D; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Karlsson S; Molecular Hematology, Lund Stem Cell Center, Lund University, Lund, Sweden.

Leukemia ; 29(11): 2221-9, 2015 Nov.

Article de En | MEDLINE | ID: mdl-25987256

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Ribonucléoprotéines / Précurseurs érythroïdes / Anémie de Blackfan-Diamond / Protéines proto-oncogènes c-mdm2 Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: Leukemia Sujet du journal: HEMATOLOGIA / NEOPLASIAS Année: 2015 Type de document: Article Pays d'affiliation: Suède

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