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Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
Kadayat, Tara Man; Song, Chanju; Shin, Somin; Magar, Til Bahadur Thapa; Bist, Ganesh; Shrestha, Aarajana; Thapa, Pritam; Na, Younghwa; Kwon, Youngjoo; Lee, Eung-Seok.
Affiliation
  • Kadayat TM; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Song C; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top5 program, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Shin S; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top5 program, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Magar TB; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Bist G; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Shrestha A; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Thapa P; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Na Y; College of Pharmacy, Cha University, Pochon 487-010, Republic of Korea.
  • Kwon Y; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top5 program, Ewha Womans University, Seoul 120-750, Republic of Korea. Electronic address: ykwon@ewha.ac.kr.
  • Lee ES; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea. Electronic address: eslee@yu.ac.kr.
Bioorg Med Chem ; 23(13): 3499-512, 2015 Jul 01.
Article de En | MEDLINE | ID: mdl-26022080

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pyridines / ADN topoisomérases de type II / ADN topoisomérases de type I / Inhibiteurs de la topoisomérase-I / Inhibiteurs de la topoisomérase-II / Antinéoplasiques Limites: Humans Langue: En Journal: Bioorg Med Chem Sujet du journal: BIOQUIMICA / QUIMICA Année: 2015 Type de document: Article

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pyridines / ADN topoisomérases de type II / ADN topoisomérases de type I / Inhibiteurs de la topoisomérase-I / Inhibiteurs de la topoisomérase-II / Antinéoplasiques Limites: Humans Langue: En Journal: Bioorg Med Chem Sujet du journal: BIOQUIMICA / QUIMICA Année: 2015 Type de document: Article