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Detection of T-Cadherin Expression in Mouse Embryos.
Rubina, K A; Smutova, V A; Semenova, M L; Poliakov, A A; Gerety, S; Wilkinson, D; Surkova, E I; Semina, E V; Sysoeva, V Yu; Tkachuk, V A.
Affiliation
  • Rubina KA; Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
  • Smutova VA; Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
  • Semenova ML; Department of Embryology, Biology Faculty, Lomonosov Moscow State University, Leninskie Gory, 1/12, 119234, Moscow, Russia.
  • Poliakov AA; Division of Developmental Neurobiology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
  • Gerety S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Wilkinson D; Division of Developmental Neurobiology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
  • Surkova EI; Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
  • Semina EV; Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
  • Sysoeva VY; Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
  • Tkachuk VA; Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
Acta Naturae ; 7(2): 87-94, 2015.
Article de En | MEDLINE | ID: mdl-26085949
ABSTRACT
The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Type d'étude: Diagnostic_studies Langue: En Journal: Acta Naturae Année: 2015 Type de document: Article Pays d'affiliation: Russie
Texte intégral
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Type d'étude: Diagnostic_studies Langue: En Journal: Acta Naturae Année: 2015 Type de document: Article Pays d'affiliation: Russie