Antioxidant activity of taxifolin: an activity-structure relationship.
J Enzyme Inhib Med Chem
; 31(4): 674-83, 2016 Aug.
Article
de En
| MEDLINE
| ID: mdl-26147349
ABSTRACT
Taxifolin is a kind of flavanonol, whose biological ability. The objectives of this study were to investigate the antioxidants and antiradical activities of taxifolin by using different in vitro bioanalytical antioxidant methods including DMPDâ(+), ABTSâ(+), [Formula see text], and DPPHâ-scavenging effects, the total antioxidant influence, reducing capabilities, and Fe(2+)-chelating activities. Taxifolin demonstrated 81.02% inhibition of linoleic acid emulsion peroxidation at 30 µg/mL concentration. At the same concentration, standard antioxidants including trolox, α-tocopherol, BHT, and BHA exhibited inhibitions of linoleic acid emulsion as 88.57, 73.88, 94.29, and 90.12%, respectively. Also, taxifolin exhibited effective DMPDâ(+), ABTSâ(+), [Formula see text], and DPPHâ-scavenging effects, reducing capabilities, and Fe(2+)-chelating effects. The results obtained from this study clearly showed that taxifolin had marked antioxidant, reducing ability, radical scavenging and metal-chelating activities. Also, this study exhibits a scientific shore for the significant antioxidant activity of taxifolin and its structure-activity insight.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Quercétine
/
Antioxydants
Langue:
En
Journal:
J Enzyme Inhib Med Chem
Sujet du journal:
BIOQUIMICA
/
QUIMICA
Année:
2016
Type de document:
Article
Pays d'affiliation:
Turquie