Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers.

Oku, Yusuke; Nishiya, Naoyuki; Shito, Toshiya; Yamamoto, Reiichiro; Yamamoto, Yasufumi; Oyama, Chihiro; Uehara, Yoshimasa

Oku, Yusuke; Nishiya, Naoyuki; Shito, Toshiya; Yamamoto, Reiichiro; Yamamoto, Yasufumi; Oyama, Chihiro; Uehara, Yoshimasa.

Affiliation

Oku Y; Department of Microbial Chemical Biology and Drug Discovery, Iwate Medical University School of Pharmaceutical Sciences, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.
Nishiya N; Department of Microbial Chemical Biology and Drug Discovery, Iwate Medical University School of Pharmaceutical Sciences, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.
Shito T; Department of Microbial Chemical Biology and Drug Discovery, Iwate Medical University School of Pharmaceutical Sciences, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.
Yamamoto R; Department of Microbial Chemical Biology and Drug Discovery, Iwate Medical University School of Pharmaceutical Sciences, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.
Yamamoto Y; Department of Microbial Chemical Biology and Drug Discovery, Iwate Medical University School of Pharmaceutical Sciences, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.
Oyama C; Department of Microbial Chemical Biology and Drug Discovery, Iwate Medical University School of Pharmaceutical Sciences, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.
Uehara Y; Department of Microbial Chemical Biology and Drug Discovery, Iwate Medical University School of Pharmaceutical Sciences, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.

FEBS Open Bio ; 5: 542-9, 2015.

Article de En | MEDLINE | ID: mdl-26199863

Mots clés

CTGF, connective tissue growth factor; Combination therapy; Dasatinib; FDA, food and drug administration; GPCR, G-protein coupled receptor; HMG-CoA, hydroxymethylglutaryl-coenzyme A; NF2, neurofibromin 2; Pazopanib; Statins; TAZ; TAZ, transcriptional coactivator with PDZ-binding motif; TEAD, TEA domain family member; YAP; YAP, yes-associated protein

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: FEBS Open Bio Année: 2015 Type de document: Article Pays d'affiliation: Japon Pays de publication: Royaume-Uni

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google