Studies on hypolipidemic agents. IV. 3-[4-(Phenylthio)benzoyl]propionic acid derivatives.
Chem Pharm Bull (Tokyo)
; 37(5): 1260-7, 1989 May.
Article
de En
| MEDLINE
| ID: mdl-2630091
ABSTRACT
2-Acetylthio-3-benzoylpropionic acid derivatives having two benzene rings or condensed-ring moieties were prepared, and tested for hypolipidemic activity in normal rats. Some of these compounds were active. 2-Acetylthio-3-[4-(phenylthio)benzoyl]propionic acid (10) and its derivatives seemed to have the most potent hypocholesterolemic activities. Compound 10 showed strong activity, especially in cholesterol-fed rats.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Thiols
/
Benzoates
/
Hypolipémiants
Limites:
Animals
Langue:
En
Journal:
Chem Pharm Bull (Tokyo)
Année:
1989
Type de document:
Article