Alpha-Tocopherol Concentration in Colostrum and Serum of Women With Premature Labor.
J Pediatr Gastroenterol Nutr
; 62(2): 348-52, 2016 Feb.
Article
de En
| MEDLINE
| ID: mdl-26334256
ABSTRACT
OBJECTIVE:
The aim of the study was to evaluate and compare the levels of alpha-tocopherol in colostrum milk and serum of mothers with premature birth, classified as severe prematurity and moderate prematurity.METHODS:
Cross-sectional study with 65 women, 18 births classified as severe prematurity (<32 weeks of gestation) and 47 as moderate prematurity (≥32 weeks of gestation). The study only included mothers without any conditions associated with pregnancy and who had a single conception without any malformation. Samples of serum and colostrum were collected during fasting in the immediate postpartum, and alpha-tocopherol was analyzed by high-performance liquid chromatography. To determine the biochemical nutritional status of vitamin E, a serum cutoff (11.6 µmol/L) was adopted. The Student t test for independent variables compared the average concentrations of alpha-tocopherol in serum and colostrum among prematurity groups. Differences were considered significant when Pâ<â0.05.RESULTS:
The alpha-tocopherol concentrations in colostrum were similar in both groups, being 34.5â±â20.2 µmol/L for women with severe prematurity and 35.1â±â16.3 µmol/L for moderate prematurity. For the serum of puerperal women with severe prematurity, alpha-tocopherol concentration was, however, lower than in women with moderate prematurity, 22.2â±â4.4 µmol/L versus 27.1â±â8.6 µmol/L (Pâ<â0.05). The serum levels of alpha-tocopherol indicated nutritional risk at 5.6% (nâ=â1) of women with severe prematurity and 4.3% (nâ=â2) for those with moderate prematurity.CONCLUSIONS:
Severe prematurity affected the levels of alpha-tocopherol in maternal serum; however, the level of prematurity did not change the concentration of vitamin E in colostrum.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Prématuré
/
État nutritionnel
/
Colostrum
/
Alpha-Tocophérol
/
Naissance prématurée
/
Travail obstétrical prématuré
Type d'étude:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limites:
Adolescent
/
Adult
/
Female
/
Humans
/
Middle aged
/
Pregnancy
Langue:
En
Journal:
J Pediatr Gastroenterol Nutr
Année:
2016
Type de document:
Article
Pays d'affiliation:
Brésil