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Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors ­ A Structural Perspective of Ligands and Mutants.
Harpsøe, Kasper; Isberg, Vignir; Tehan, Benjamin G; Weiss, Dahlia; Arsova, Angela; Marshall, Fiona H; Bräuner-Osborne, Hans; Gloriam, David E.
Affiliation
  • Harpsøe K; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark.
  • Isberg V; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark.
  • Tehan BG; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, AL7 3AX, UK.
  • Weiss D; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, AL7 3AX, UK.
  • Arsova A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark.
  • Marshall FH; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, AL7 3AX, UK.
  • Bräuner-Osborne H; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark.
  • Gloriam DE; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark.
Sci Rep ; 5: 13869, 2015 Sep 11.
Article de En | MEDLINE | ID: mdl-26359761

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteurs métabotropes au glutamate / Ligands / Mutation Limites: Humans Langue: En Journal: Sci Rep Année: 2015 Type de document: Article Pays d'affiliation: Danemark Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteurs métabotropes au glutamate / Ligands / Mutation Limites: Humans Langue: En Journal: Sci Rep Année: 2015 Type de document: Article Pays d'affiliation: Danemark Pays de publication: Royaume-Uni