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New carbocyclic N(6)-substituted adenine and pyrimidine nucleoside analogues with a bicyclo[2.2.1]heptane fragment as sugar moiety; synthesis, antiviral, anticancer activity and X-ray crystallography.
Tanase, Constantin I; Draghici, Constantin; Cojocaru, Ana; Galochkina, Anastasia V; Orshanskaya, Jana R; Zarubaev, Vladimir V; Shova, Sergiu; Enache, Cristian; Maganu, Maria.
Affiliation
  • Tanase CI; National Institute for Chemical-Pharmaceutical Research and Development, 112 Vitan Av., 031299 Bucharest 3, Romania. Electronic address: cvtanase@gmail.com.
  • Draghici C; Organic Chemistry Center 'C.D.Nenitescu, 202 B Splaiul Independentei, Bucharest 060023, Romania.
  • Cojocaru A; National Institute for Chemical-Pharmaceutical Research and Development, 112 Vitan Av., 031299 Bucharest 3, Romania.
  • Galochkina AV; Influenza Research Institute, Dept. Chemotherapy, 15/17 Prof. Popova Str., St. Petersburg 197376, Russian Federation. Electronic address: nastyagalochkina@yandex.ru.
  • Orshanskaya JR; Influenza Research Institute, Dept. Chemotherapy, 15/17 Prof. Popova Str., St. Petersburg 197376, Russian Federation. Electronic address: deina89@mail.ru.
  • Zarubaev VV; Influenza Research Institute, Dept. Chemotherapy, 15/17 Prof. Popova Str., St. Petersburg 197376, Russian Federation. Electronic address: zarubaev@influenza.spb.ru.
  • Shova S; Institute of Macromolecular Chemistry 'Petru Poni', Iasi, Romania.
  • Enache C; Central Laboratory for Phytosanitary Quarantine, 11, Voluntari Blvd., 077190 Voluntari, Romania.
  • Maganu M; Organic Chemistry Center 'C.D.Nenitescu, 202 B Splaiul Independentei, Bucharest 060023, Romania.
Bioorg Med Chem ; 23(19): 6346-54, 2015 Oct 01.
Article de En | MEDLINE | ID: mdl-26361736
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Antiviraux / Nucléosides pyrimidiques / Composés bicycliques pontés / Nucléotides adényliques / Antinéoplasiques Limites: Animals / Humans Langue: En Journal: Bioorg Med Chem Sujet du journal: BIOQUIMICA / QUIMICA Année: 2015 Type de document: Article Pays de publication: Royaume-Uni
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Antiviraux / Nucléosides pyrimidiques / Composés bicycliques pontés / Nucléotides adényliques / Antinéoplasiques Limites: Animals / Humans Langue: En Journal: Bioorg Med Chem Sujet du journal: BIOQUIMICA / QUIMICA Année: 2015 Type de document: Article Pays de publication: Royaume-Uni