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Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.
Spinks, Daniel; Smith, Victoria; Thompson, Stephen; Robinson, David A; Luksch, Torsten; Smith, Alasdair; Torrie, Leah S; McElroy, Stuart; Stojanovski, Laste; Norval, Suzanne; Collie, Iain T; Hallyburton, Irene; Rao, Bhavya; Brand, Stephen; Brenk, Ruth; Frearson, Julie A; Read, Kevin D; Wyatt, Paul G; Gilbert, Ian H.
Affiliation
  • Spinks D; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Smith V; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Thompson S; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Robinson DA; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Luksch T; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Smith A; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Torrie LS; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • McElroy S; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Stojanovski L; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Norval S; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Collie IT; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Hallyburton I; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Rao B; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Brand S; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Brenk R; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Frearson JA; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Read KD; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Wyatt PG; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.
  • Gilbert IH; Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK. i.h.gilbert@dundee.ac.uk.
ChemMedChem ; 10(11): 1821-36, 2015 Nov.
Article de En | MEDLINE | ID: mdl-26395087
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Trypanosoma brucei brucei / Acyltransferases / Antienzymes / Bibliothèques de petites molécules / Découverte de médicament Limites: Humans Langue: En Journal: ChemMedChem Sujet du journal: FARMACOLOGIA / QUIMICA Année: 2015 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Allemagne
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Trypanosoma brucei brucei / Acyltransferases / Antienzymes / Bibliothèques de petites molécules / Découverte de médicament Limites: Humans Langue: En Journal: ChemMedChem Sujet du journal: FARMACOLOGIA / QUIMICA Année: 2015 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Allemagne