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Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes.
Xie, Yuchao; McGill, Mitchell R; Du, Kuo; Dorko, Kenneth; Kumer, Sean C; Schmitt, Timothy M; Ding, Wen-Xing; Jaeschke, Hartmut.
Affiliation
  • Xie Y; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • McGill MR; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Du K; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Dorko K; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Kumer SC; Department of Surgery, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Schmitt TM; Department of Surgery, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Ding WX; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Jaeschke H; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA. Electronic address: hjaeschke@kumc.edu.
Toxicol Appl Pharmacol ; 289(2): 213-22, 2015 Dec 01.
Article de En | MEDLINE | ID: mdl-26431796
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Mitochondries du foie / Hépatocytes / Protéines mitochondriales / Lésions hépatiques dues aux substances / Foie / Acétanilides Limites: Animals / Humans Langue: En Journal: Toxicol Appl Pharmacol Année: 2015 Type de document: Article Pays d'affiliation: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Mitochondries du foie / Hépatocytes / Protéines mitochondriales / Lésions hépatiques dues aux substances / Foie / Acétanilides Limites: Animals / Humans Langue: En Journal: Toxicol Appl Pharmacol Année: 2015 Type de document: Article Pays d'affiliation: États-Unis d'Amérique