Cost-effectiveness analysis of sacral nerve stimulation as treatment for severe irritable bowel syndrome.
Colorectal Dis
; 18(1): O30-6, 2016 Jan.
Article
de En
| MEDLINE
| ID: mdl-26466156
ABSTRACT
AIM:
Early results from sacral nerve stimulation (SNS) for severe irritable bowel syndrome (IBS) are promising but estimates of cost-effectiveness are lacking. Our object was to perform a cost-effectiveness analysis for SNS as an alternative to no treatment of IBS.METHOD:
This retrospective analysis was based on the results from a randomized controlled crossover study with a cost-utility analysis performed on patient-level data and modelling of censored data over a projected period of time of up to 20 years. The analysis was conducted on an intention-to-treat approach. For estimation of the uncertainty of the incremental cost-effectiveness ratio a bias corrected bootstrap analysis was performed.RESULTS:
Cost-effectiveness was not reached for 4 years after permanent implantation (£31 270 per quality-adjusted life years), which was the upper limit for patient follow-up, but our data imply a cost-effectiveness from a 7-year perspective onwards.CONCLUSION:
The study indicates the SNS treatment for IBS is cost effective from a 7-year perspective onwards.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Électrothérapie
/
Analyse coût-bénéfice
/
Syndrome du côlon irritable
/
Plexus lombosacral
Type d'étude:
Health_economic_evaluation
/
Observational_studies
Aspects:
Patient_preference
Limites:
Humans
Pays/Région comme sujet:
Europa
Langue:
En
Journal:
Colorectal Dis
Sujet du journal:
GASTROENTEROLOGIA
Année:
2016
Type de document:
Article
Pays d'affiliation:
Danemark