Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer.

Amatu, Alessio; Somaschini, Alessio; Cerea, Giulio; Bosotti, Roberta; Valtorta, Emanuele; Buonandi, Pasquale; Marrapese, Giovanna; Veronese, Silvio; Luo, David; Hornby, Zachary; Multani, Pratik; Murphy, Danielle; Shoemaker, Robert; Lauricella, Calogero; Giannetta, Laura; Maiolani, Martina; Vanzulli, Angelo; Ardini, Elena; Galvani, Arturo; Isacchi, Antonella; Sartore-Bianchi, Andrea; Siena, Salvatore

Amatu, Alessio; Somaschini, Alessio; Cerea, Giulio; Bosotti, Roberta; Valtorta, Emanuele; Buonandi, Pasquale; Marrapese, Giovanna; Veronese, Silvio; Luo, David; Hornby, Zachary; Multani, Pratik; Murphy, Danielle; Shoemaker, Robert; Lauricella, Calogero; Giannetta, Laura; Maiolani, Martina; Vanzulli, Angelo; Ardini, Elena; Galvani, Arturo; Isacchi, Antonella; Sartore-Bianchi, Andrea; Siena, Salvatore.

Affiliation

Amatu A; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Somaschini A; Business Unit Oncology, Nerviano Medical Sciences Srl, Viale Pasteur 10, 20014 Nerviano, MI, Italy.
Cerea G; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Bosotti R; Business Unit Oncology, Nerviano Medical Sciences Srl, Viale Pasteur 10, 20014 Nerviano, MI, Italy.
Valtorta E; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Buonandi P; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Marrapese G; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Veronese S; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Luo D; Ignyta, Inc., 11111 Flintkote Avenue, San Diego, CA 92121, USA.
Hornby Z; Ignyta, Inc., 11111 Flintkote Avenue, San Diego, CA 92121, USA.
Multani P; Ignyta, Inc., 11111 Flintkote Avenue, San Diego, CA 92121, USA.
Murphy D; Ignyta, Inc., 11111 Flintkote Avenue, San Diego, CA 92121, USA.
Shoemaker R; Ignyta, Inc., 11111 Flintkote Avenue, San Diego, CA 92121, USA.
Lauricella C; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Giannetta L; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Maiolani M; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Vanzulli A; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Ardini E; Business Unit Oncology, Nerviano Medical Sciences Srl, Viale Pasteur 10, 20014 Nerviano, MI, Italy.
Galvani A; Business Unit Oncology, Nerviano Medical Sciences Srl, Viale Pasteur 10, 20014 Nerviano, MI, Italy.
Isacchi A; Business Unit Oncology, Nerviano Medical Sciences Srl, Viale Pasteur 10, 20014 Nerviano, MI, Italy.
Sartore-Bianchi A; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.
Siena S; Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.

Br J Cancer ; 113(12): 1730-4, 2015 Dec 22.

Article de En | MEDLINE | ID: mdl-26633560

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Aspartate carbamoyltransferase / Benzamides / Carbamoyl-phosphate synthase (glutamine-hydrolyzing) / Tumeurs colorectales / Réarrangement des gènes / Récepteurs à activité tyrosine kinase / Dihydro-orotase / Indazoles / Antinéoplasiques Type d'étude: Prognostic_studies Limites: Female / Humans / Middle aged Langue: En Journal: Br J Cancer Année: 2015 Type de document: Article Pays d'affiliation: Italie Pays de publication: Royaume-Uni

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