Primary tumour characteristics predict the invasiveness of lymph node metastases in papillary thyroid carcinoma patients.
J Laryngol Otol
; 130(3): 302-8, 2016 Mar.
Article
de En
| MEDLINE
| ID: mdl-26669829
ABSTRACT
OBJECTIVE:
This study evaluated whether primary tumour characteristics are associated with specific features of metastatic lymph nodes in papillary thyroid carcinoma patients.METHOD:
A retrospective review of 411 patients with pathologically diagnosed cervical lymph node metastasis was conducted.RESULTS:
A metastatic lymph node focus size of at least 2 mm was independently associated with a primary tumour size of at least 1 cm (hazard ratio 1.962) and with male sex (hazard ratio 1.947). A number of at least five lymph node metastases was independently associated with a primary tumour size of at least 1 cm (hazard ratio 2.863), extrathyroidal extension (hazard ratio 1.737) and male sex (hazard ratio 1.689). Extranodal extension was independently associated with a primary tumour size of at least 1 cm (hazard ratio 2.288), extrathyroidal extension (2.201) and male sex (hazard ratio 1.733).CONCLUSION:
Primary papillary thyroid carcinoma characteristics are related to the pathological features of lymph node metastases.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs de la thyroïde
/
Carcinomes
Type d'étude:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
J Laryngol Otol
Sujet du journal:
OTORRINOLARINGOLOGIA
Année:
2016
Type de document:
Article