Epicardial fat thickness as associated with left ventricular myocardial performance in patients with newly diagnosed hypertension.
Turk Kardiyol Dern Ars
; 43(8): 705-13, 2015 Dec.
Article
de En
| MEDLINE
| ID: mdl-26717332
ABSTRACT
OBJECTIVE:
Epicardial fat thickness (EFth) is associated with both left ventricular hypertrophy (LVH) and diastolic dysfunction. However, the effect of EFth on myocardial performance is not known. The aim of this study was to investigate the relationship between EFth and tissue Doppler myocardial performance index (TD-MPI), which incorporates both systolic and diastolic left ventricular (LV) function, in newly diagnosed hypertension (HT) patients.METHODS:
A total of 314 consecutive, newly diagnosed HT patients were prospectively included (mean age 51.9±1.7 years). EFth was measured perpendicularly on the free wall of the right ventricle at the end of the systole in 2 echocardiographic views (parasternal short and long axis). Myocardial performance index (MPI) was calculated using tissue Doppler (TD) echocardiography. Patients were divided into 2 groups according to median TD-MPI levels (TD-MPIlow and TD-MPIhigh).RESULTS:
EFth values of the TD-MPIhigh group were higher than those of the TD-MPIlow group (p<0.05). Patients in the TD-MPIhigh group also had higher age, body mass index, systolic blood pressure (SBP), diastolic blood pressure (DBP), left ventricular mass index (LVMI), E/A ratio, and aortic distensibility, compared with the TD-MPIlow group (p<0.05 for all). Multivariate linear regression analysis showed that TD-MPI was independently associated with age (ß=0.089, p=0.012), LVMI (ß=0.090, p=0.05), E/A (ß=-0.118, p=0.005), and EFth (ß=0.432, p<0.001).CONCLUSION:
TD-MPI was independently associated with EFth in patients with newly diagnosed HT. EFth may be used as a predictor of impaired LV global functions in patients with normal left ventricular ejection fraction (LVEF) and newly diagnosed HT.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Péricarde
/
Tissu adipeux
/
Fonction ventriculaire gauche
/
Hypertension artérielle
Type d'étude:
Diagnostic_studies
/
Risk_factors_studies
Limites:
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Turk Kardiyol Dern Ars
Sujet du journal:
CARDIOLOGIA
Année:
2015
Type de document:
Article
Pays d'affiliation:
Turquie