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Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure-Activity Relationship at AMPA Receptors.
Larsen, Anja Probst; Francotte, Pierre; Frydenvang, Karla; Tapken, Daniel; Goffin, Eric; Fraikin, Pierre; Caignard, Daniel-Henri; Lestage, Pierre; Danober, Laurence; Pirotte, Bernard; Kastrup, Jette Sandholm.
Affiliation
  • Larsen AP; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken, 2, DK-2100 Copenhagen, Denmark.
  • Francotte P; Department of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liege , Avenue de l'Hôpital, 1, B36, B-4000 Liège, Belgium.
  • Frydenvang K; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken, 2, DK-2100 Copenhagen, Denmark.
  • Tapken D; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken, 2, DK-2100 Copenhagen, Denmark.
  • Goffin E; Department of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liege , Avenue de l'Hôpital, 1, B36, B-4000 Liège, Belgium.
  • Fraikin P; Department of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liege , Avenue de l'Hôpital, 1, B36, B-4000 Liège, Belgium.
  • Caignard DH; Institut de Recherches Servier , Chemin de Ronde, 125, F-78290 Croissy-sur-Seine, France.
  • Lestage P; Institut de Recherches Servier , Chemin de Ronde, 125, F-78290 Croissy-sur-Seine, France.
  • Danober L; Institut de Recherches Servier , Chemin de Ronde, 125, F-78290 Croissy-sur-Seine, France.
  • Pirotte B; Department of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liege , Avenue de l'Hôpital, 1, B36, B-4000 Liège, Belgium.
  • Kastrup JS; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken, 2, DK-2100 Copenhagen, Denmark.
ACS Chem Neurosci ; 7(3): 378-90, 2016 Mar 16.
Article de En | MEDLINE | ID: mdl-26771108
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Benzothiadiazines / Récepteur de l'AMPA Limites: Animals Langue: En Journal: ACS Chem Neurosci Année: 2016 Type de document: Article Pays d'affiliation: Danemark Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Benzothiadiazines / Récepteur de l'AMPA Limites: Animals Langue: En Journal: ACS Chem Neurosci Année: 2016 Type de document: Article Pays d'affiliation: Danemark Pays de publication: États-Unis d'Amérique