Insights into Complex Oxidation during BE-7585A Biosynthesis: Structural Determination and Analysis of the Polyketide Monooxygenase BexE.

Jackson, David R; Yu, Xia; Wang, Guojung; Patel, Avinash B; Calveras, Jordi; Barajas, Jesus F; Sasaki, Eita; Metsä-Ketelä, Mikko; Liu, Hung-Wen; Rohr, Jürgen; Tsai, Shiou-Chuan

Jackson, David R; Yu, Xia; Wang, Guojung; Patel, Avinash B; Calveras, Jordi; Barajas, Jesus F; Sasaki, Eita; Metsä-Ketelä, Mikko; Liu, Hung-Wen; Rohr, Jürgen; Tsai, Shiou-Chuan.

Affiliation

Jackson DR; Department of Molecular Biology and Biochemistry, Department of Chemistry, and Department of Pharmaceutical Sciences, University of California , Irvine, California 92697, United States.
Yu X; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky , Lexington, Kentucky 40536, United States.
Wang G; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky , Lexington, Kentucky 40536, United States.
Patel AB; Department of Molecular Biology and Biochemistry, Department of Chemistry, and Department of Pharmaceutical Sciences, University of California , Irvine, California 92697, United States.
Calveras J; Division of Medicinal Chemistry, College of Pharmacy and Department of Chemistry, University of Texas at Austin , Austin, Texas 78712, United States.
Barajas JF; Department of Molecular Biology and Biochemistry, Department of Chemistry, and Department of Pharmaceutical Sciences, University of California , Irvine, California 92697, United States.
Sasaki E; Division of Medicinal Chemistry, College of Pharmacy and Department of Chemistry, University of Texas at Austin , Austin, Texas 78712, United States.
Metsä-Ketelä M; Department of Biochemistry, University of Turku , 20014 Turku, Finland.
Liu HW; Division of Medicinal Chemistry, College of Pharmacy and Department of Chemistry, University of Texas at Austin , Austin, Texas 78712, United States.
Rohr J; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky , Lexington, Kentucky 40536, United States.
Tsai SC; Department of Molecular Biology and Biochemistry, Department of Chemistry, and Department of Pharmaceutical Sciences, University of California , Irvine, California 92697, United States.

ACS Chem Biol ; 11(4): 1137-47, 2016 Apr 15.

Article de En | MEDLINE | ID: mdl-26813028

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Polyketide synthases / Thiosucres Langue: En Journal: ACS Chem Biol Année: 2016 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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