Is the effect of topical intranasal steroids on obstructive adenoids transient or long-lasting? Case series and systematic review of literature.
J Laryngol Otol
; 130(4): 357-62, 2016 Apr.
Article
de En
| MEDLINE
| ID: mdl-26847580
ABSTRACT
OBJECTIVES:
To study and review the short- and long-term effects of intranasal steroids on obstructive adenoids.METHODS:
In this prospective cohort study, 19 children previously treated with mometasone furoate for 3 months were contacted at 3, 6 and 12 months after cessation of treatment. Main outcome measures included change in severity of nasal obstruction, allergic rhinitis and obstructive symptoms. A systematic review of literature was also performed.RESULTS:
By one year, 25 per cent of patients required adenoidectomy; the remaining children had no significant change in clinical score (p = 0.464), obstruction severity (p = 0.191) or allergic symptoms (p = 0.284). Fourteen pertinent studies were identified; all but one study showed improvement in the patients' symptoms and/or degree of obstruction. Two studies with follow up reaching 25 months showed positive effects.CONCLUSION:
The short-term positive effect of some intranasal steroids on obstructive adenoids seems to persist in a significant number of patients after the cessation of treatment.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tonsilles pharyngiennes
/
Obstruction nasale
/
Furoate de mométasone
/
Anti-inflammatoires
Type d'étude:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Systematic_reviews
Limites:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Langue:
En
Journal:
J Laryngol Otol
Sujet du journal:
OTORRINOLARINGOLOGIA
Année:
2016
Type de document:
Article
Pays d'affiliation:
Liban