Pseudouridines in U2 snRNA stimulate the ATPase activity of Prp5 during spliceosome assembly.

Wu, Guowei; Adachi, Hironori; Ge, Junhui; Stephenson, David; Query, Charles C; Yu, Yi-Tao

Wu, Guowei; Adachi, Hironori; Ge, Junhui; Stephenson, David; Query, Charles C; Yu, Yi-Tao.

Affiliation

Wu G; Department of Biochemistry and Biophysics, Center for RNA Biology, The Rochester Aging Research (RoAR) Center, University of Rochester Medical Center, Rochester, NY, USA.
Adachi H; Department of Biochemistry and Biophysics, Center for RNA Biology, The Rochester Aging Research (RoAR) Center, University of Rochester Medical Center, Rochester, NY, USA.
Ge J; Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Stephenson D; Department of Biochemistry and Biophysics, Center for RNA Biology, The Rochester Aging Research (RoAR) Center, University of Rochester Medical Center, Rochester, NY, USA.
Query CC; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Yu YT; Department of Biochemistry and Biophysics, Center for RNA Biology, The Rochester Aging Research (RoAR) Center, University of Rochester Medical Center, Rochester, NY, USA yitao_yu@urmc.rochester.edu.

EMBO J ; 35(6): 654-67, 2016 Mar 15.

Article de En | MEDLINE | ID: mdl-26873591

Sujet(s)
Mots clés

Prp5 ATPase; U2 snRNA; pseudouridylation; spliceosome assembly; splicing

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pseudouridine / Saccharomyces cerevisiae / Petit ARN nucléaire / Épissage des ARN / Splicéosomes / Protéines de Saccharomyces cerevisiae / DEAD-box RNA helicases Langue: En Journal: EMBO J Année: 2016 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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