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Impact of Cytochrome P450 2D6 Function on the Chiral Blood Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine (MDMA) and Its Phase I and II Metabolites in Humans.
Steuer, Andrea E; Schmidhauser, Corina; Tingelhoff, Eva H; Schmid, Yasmin; Rickli, Anna; Kraemer, Thomas; Liechti, Matthias E.
Affiliation
  • Steuer AE; Department of Forensic Pharmacology & Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland.
  • Schmidhauser C; Department of Forensic Pharmacology & Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland.
  • Tingelhoff EH; Department of Forensic Pharmacology & Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland.
  • Schmid Y; Psychopharmacology Research, Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
  • Rickli A; Psychopharmacology Research, Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
  • Kraemer T; Department of Forensic Pharmacology & Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland.
  • Liechti ME; Psychopharmacology Research, Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
PLoS One ; 11(3): e0150955, 2016.
Article de En | MEDLINE | ID: mdl-26967321

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Plasma sanguin / N-Méthyl-3,4-méthylènedioxy-amphétamine / Cytochrome P-450 CYP2D6 Type d'étude: Clinical_trials / Prognostic_studies Limites: Humans Langue: En Journal: PLoS One Sujet du journal: CIENCIA / MEDICINA Année: 2016 Type de document: Article Pays d'affiliation: Suisse

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Plasma sanguin / N-Méthyl-3,4-méthylènedioxy-amphétamine / Cytochrome P-450 CYP2D6 Type d'étude: Clinical_trials / Prognostic_studies Limites: Humans Langue: En Journal: PLoS One Sujet du journal: CIENCIA / MEDICINA Année: 2016 Type de document: Article Pays d'affiliation: Suisse