Reproducibility of myocardial T1 and T2 relaxation time measurement using slice-interleaved T1 and T2 mapping sequences.
J Magn Reson Imaging
; 44(5): 1159-1167, 2016 11.
Article
de En
| MEDLINE
| ID: mdl-27043156
ABSTRACT
PURPOSE:
To assess measurement reproducibility and image quality of myocardial T1 and T2 maps using free-breathing slice-interleaved T1 and T2 mapping sequences at 1.5 Tesla (T). MATERIALS ANDMETHODS:
Eleven healthy subjects (33 ± 16 years; 6 males) underwent a slice-interleaved T1 and T2 mapping test/retest cardiac MR study at 1.5T on 2 days. For each day, subjects were imaged in two sessions with removal out of the magnet and repositioning before the subsequent session. We studied measurement reproducibility as well as the required sample size for sufficient statistical power to detect a predefined change in T1 and T2 . In a separate prospective study, we assessed T1 and T2 map image quality in 241 patients (54 ± 15 years; 73 women) with known/suspected cardiovascular disease referred for clinical cardiac MR. A subjective quality score was used to assess a segment-based image quality.RESULTS:
In the healthy cohort, the slice-interleaved T1 measurements were highly reproducible, with global coefficients of variation (CVs) of 2.4% between subjects, 2.1% between days, and 1.7% between sessions. Slice-interleaved T2 mapping sequences provided similar reproducibility with global CVs of 7.2% between subjects, 6.3% between days, and 5.0 between sessions. A lower variability resulted in a reduction of the required number of subjects to achieve a certain statistical power when compared with other T1 mapping sequences. In the subjective image quality assessment, >80% of myocardial segments had interpretable data.CONCLUSION:
Slice-interleaved T1 and T2 mapping sequences yield highly reproducible T1 and T2 measurements with >80% of interpretable myocardial segments. J. Magn. Reson. Imaging 2016;441159-1167.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Traitement du signal assisté par ordinateur
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Imagerie par résonance magnétique
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Interprétation d'images assistée par ordinateur
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Techniques d'imagerie cardiaque
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Coeur
Type d'étude:
Diagnostic_studies
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Evaluation_studies
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Observational_studies
Limites:
Adult
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Female
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Humans
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Male
Langue:
En
Journal:
J Magn Reson Imaging
Sujet du journal:
DIAGNOSTICO POR IMAGEM
Année:
2016
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique