Hashimoto's Thyroiditis in South Indian Centre.
Indian J Pediatr
; 83(11): 1227-1231, 2016 Nov.
Article
de En
| MEDLINE
| ID: mdl-27094775
ABSTRACT
OBJECTIVE:
To describe the clinical and investigatory profile of children with Hashimoto's thyroiditis (HT) presenting to the thyroid clinic of a referral children's hospital and study the course of children diagnosed as HT over a period of 6 mo.METHODS:
Children aged 5-12 y with HT were recruited, their clinical and biochemical details were assessed and were started on standard therapy and followed up for a period of 6 mo.RESULTS:
Ninety-seven children (89 goitrous and 8 atrophic form) with mean age 9.90 ± 1.76 y; MF 15.4 were recruited; 55.7 % were asymptomatic;14.2 % had familial clustering. The mean height, weight and BMI for age Z-scores were -1.0 ± 1.0, -0.8 ± 0.9 and -0.5 ± 1.1 respectively. 16.4 % had short stature; 4.1 % had obesity; 72.2 % had grade 2 goitre. 73.4 %, 13.2 %, 10.3 % and 3.1 % had overt hypothyroidism, sub-clinical hypothyroidism, euthyroidism and hyperthyroidism, respectively. On follow up, 38.5 % of euthyroid and 80 % of sub-clinical hypothyroid children developed overt hypothyroidism. Thyrotoxic symptoms resolved in all three Hashitoxic children by 6 mo.CONCLUSIONS:
A female preponderance, less familial clustering, higher paucity of clinical manifestations and quick progression to hypothyroidism (in those without) were noted in the present series.Mots clés
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Maladie de Hashimoto
Limites:
Child
/
Female
/
Humans
/
Male
Langue:
En
Journal:
Indian J Pediatr
Année:
2016
Type de document:
Article
Pays d'affiliation:
Inde