Discovery of a novel NEDD8 Activating Enzyme Inhibitor with Piperidin-4-amine Scaffold by Structure-Based Virtual Screening.

Lu, Peng; Liu, Xiaoxin; Yuan, Xinrui; He, Minfang; Wang, Yubin; Zhang, Qi; Ouyang, Ping-Kai

Lu, Peng; Liu, Xiaoxin; Yuan, Xinrui; He, Minfang; Wang, Yubin; Zhang, Qi; Ouyang, Ping-Kai.

Affiliation

Lu P; School of Pharmaceutical Sciences, Nanjing Tech University , No. 5 Xinmofan Road, Nanjing 210009, People's Republic of China.
Liu X; School of Pharmaceutical Sciences, Nanjing Tech University , No. 5 Xinmofan Road, Nanjing 210009, People's Republic of China.
Yuan X; School of Pharmaceutical Sciences, Nanjing Tech University , No. 5 Xinmofan Road, Nanjing 210009, People's Republic of China.
He M; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University , No. 5 Xinmofan Road, Nanjing 210009, People's Republic of China.
Wang Y; School of Pharmaceutical Sciences, Nanjing Tech University , No. 5 Xinmofan Road, Nanjing 210009, People's Republic of China.
Zhang Q; School of Pharmaceutical Sciences, Nanjing Tech University , No. 5 Xinmofan Road, Nanjing 210009, People's Republic of China.
Ouyang PK; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University , No. 5 Xinmofan Road, Nanjing 210009, People's Republic of China.

ACS Chem Biol ; 11(7): 1901-7, 2016 07 15.

Article de En | MEDLINE | ID: mdl-27135934

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pipéridines / Ubiquitin-conjugating enzymes / Antienzymes Type d'étude: Diagnostic_studies / Prognostic_studies / Screening_studies Limites: Animals / Humans Langue: En Journal: ACS Chem Biol Année: 2016 Type de document: Article Pays de publication: États-Unis d'Amérique

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