Effects of haemoglobin levels on the sublingual microcirculation in pregnant women.
Clin Hemorheol Microcirc
; 64(2): 205-212, 2016 Nov 25.
Article
de En
| MEDLINE
| ID: mdl-27258200
ABSTRACT
Anemia in pregnant women is associated with increased maternal and perinatal mortality and represents an important economic burden in many developing countries. Our goal was to evaluate the impact of anemia on the capillary network during pregnancy. Therefore, we compared microcirculatory parameters of anemic pregnant study participants to that of non-anemic pregnant women employing sublingual microcirculation video imaging technology and novel automated video analysis software.Non-anemic (nâ=â7) and anemic (nâ=â44) pregnant women were enrolled in the study at second and third trimesters. Video imaging was applied to the sublingual mucosal surface in five visual fields. The resultant videos were analyzed automatically, avoiding observer bias. Total vessel density (TVD), perfused vessel density (PVD) and proportion of perfused vessels (PPV) were calculated by the software. Both, mean TVD and PVD were significantly increased in the anemic pregnant group, while the PPV was not significantly different. Significant negative correlations were observed between haemoglobin (Hb) levels and both, TVD and PVD. Haemoglobin level seems to play an important determinant role in restructuring the capillary network. An effect that could compensate the impaired tissue oxygen delivery associated with anemia during pregnancy.
Mots clés
Recherche sur Google
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Hémoglobines
/
Absorption par la muqueuse orale
Limites:
Adult
/
Female
/
Humans
/
Pregnancy
Langue:
En
Journal:
Clin Hemorheol Microcirc
Sujet du journal:
ANGIOLOGIA
/
HEMATOLOGIA
Année:
2016
Type de document:
Article
Pays d'affiliation:
Égypte