The effect of female sex hormone supplementation on tendon in pre and postmenopausal women: A systematic review.
J Musculoskelet Neuronal Interact
; 16(2): 92-104, 2016 06 01.
Article
de En
| MEDLINE
| ID: mdl-27282453
ABSTRACT
OBJECTIVES:
Oestrogen deprivation has been shown to have a negative effect on connective tissue and its turnover. A link may exist between supplemental oestrogen, preservation of tendon collagen and less tendon abnormality. The aim was to determine the effects of female sex hormone supplementation (FSHS) on tendon.METHODS:
A systematic search of nine key health databases; Medline, CINAHL, EMBASE, SPORTDiscus, AUSPORT and AMI, Cochrane Library, SafetyLit and PEDro was completed (to Feb 24, 2016). The search yielded 6378 records using terms relating to hormone (oestrogen, estrogen, hormone replacement therapy, HRT, estrogen therapy, oestrogen therapy, oral contraceptive pill) and tendon. Quality assessment, data extraction and data synthesis of included papers was undertaken.RESULTS:
Low level of evidence for all outcomes; no positive or negative link between FSHS and molecular, mechanical and morphological tendon response outcomes, and the addition of exercise to FSHS, had minimal effects on tendon CSA.CONCLUSIONS:
The effect of oestrogen supplementation on tendon is contradictory and inconsistent. This review suggests there is a need for further studies to understand the effects of FSHS on tendon tissue at a mechanical, morphological and molecular level.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tendons
/
Hormonothérapie substitutive
Type d'étude:
Systematic_reviews
Limites:
Female
/
Humans
Langue:
En
Journal:
J Musculoskelet Neuronal Interact
Sujet du journal:
FISIOLOGIA
/
NEUROLOGIA
/
ORTOPEDIA
Année:
2016
Type de document:
Article
Pays d'affiliation:
Australie