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A Cap for Every Occasion: Alternative eIF4F Complexes.
Ho, J J David; Lee, Stephen.
Affiliation
  • Ho JJD; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL 31336, USA; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 31336, USA.
  • Lee S; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL 31336, USA; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 31336, USA. Electronic address: stephenlee@med.miami.edu.
Trends Biochem Sci ; 41(10): 821-823, 2016 10.
Article de En | MEDLINE | ID: mdl-27283511
The eukaryotic translation initiation factor 4F (eIF4F) has become essentially synonymous with 5' cap-dependent mRNA translation. Recent studies demonstrate that cells assemble variants of eIF4F to produce adaptive, cap-dependent translatomes during physiological conditions that inhibit eIF4F. These findings challenge us to reassess classical perceptions of cellular translational pathways.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Schizosaccharomyces / Biosynthèse des protéines / ARN messager / Trypanosomatina / Facteur-4E d'initiation eucaryote / Facteur-4F d'initiation eucaryote Limites: Animals / Humans Langue: En Journal: Trends Biochem Sci Année: 2016 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Schizosaccharomyces / Biosynthèse des protéines / ARN messager / Trypanosomatina / Facteur-4E d'initiation eucaryote / Facteur-4F d'initiation eucaryote Limites: Animals / Humans Langue: En Journal: Trends Biochem Sci Année: 2016 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni