Effect of glucocorticoid combined with gamma globulin in treatment of children with myasthenia gravis and its effects on immune globulin and complement of children.
Eur Rev Med Pharmacol Sci
; 20(11): 2404-8, 2016 06.
Article
de En
| MEDLINE
| ID: mdl-27338067
ABSTRACT
OBJECTIVE:
To discuss the effects glucocorticoid combined with gamma globulins in the treatment of children with myasthenia gravis and its effects on immune globulin and complement of children. PATIENTS ANDMETHODS:
Clinical data of 70 cases of childhood myasthenia gravis in this hospital were retrospectively analyzed. These cases were randomly divided into observation group and control group. For observation group, there were methylprednisolone and gamma globulins while the only methylprednisolone in the control group. The clinical effects and changes in immune globulin and complement of two groups were observed.RESULTS:
The total effective rate for observation group was 94.3% and 74.3% for the control group, and this difference was statistically significant (p < 0.05) The time for relief of symptoms (6.55 ± 1.35 days) and total hospital stay (17.15 ± 3.65 days) in observation group was apparently shorter than the control group, with statistical significance (p < 0.05).CONCLUSIONS:
Glucocorticoid and gamma globulin can improve the symptoms and achieve satisfying clinical effects for the treatment of myasthenia gravis in children. Thus, it is valuable for further popularization and application.
Recherche sur Google
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Gammaglobulines
/
Méthylprednisolone
/
Glucocorticoïdes
/
Myasthénie
Type d'étude:
Observational_studies
/
Risk_factors_studies
Limites:
Child
/
Humans
Langue:
En
Journal:
Eur Rev Med Pharmacol Sci
Sujet du journal:
FARMACOLOGIA
/
TOXICOLOGIA
Année:
2016
Type de document:
Article