Separation of mono- and di-PEGylate of exenatide and resolution of positional isomers of mono-PEGylates by preparative ion exchange chromatography.

Nguyen, Ngoc-Thanh Thi; Lee, Jae Sun; Yun, Soi; Lee, E K

Nguyen, Ngoc-Thanh Thi; Lee, Jae Sun; Yun, Soi; Lee, E K.

Affiliation

Nguyen NT; Dept. of Bionano Engineering, Hanyang University-ERICA, Ansan 15588, Republic of Korea.
Lee JS; Dept. of Bionano Engineering, Hanyang University-ERICA, Ansan 15588, Republic of Korea.
Yun S; Dept. of Bionano Engineering, Hanyang University-ERICA, Ansan 15588, Republic of Korea.
Lee EK; Dept. of Bionano Engineering, Hanyang University-ERICA, Ansan 15588, Republic of Korea. Electronic address: eklee@hanyang.ac.kr.

J Chromatogr A ; 1457: 88-96, 2016 Jul 29.

Article de En | MEDLINE | ID: mdl-27363735

Sujet(s)
Mots clés

Cation exchange chromatography; Exenatide; Mono-PEGylation; PEG-maleimide; Peptide analogs; Positional isomers

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Peptides / Polyéthylène glycols / Venins / Hypoglycémiants Langue: En Journal: J Chromatogr A Année: 2016 Type de document: Article

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