Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design.

Broad, John; Maurel, Damien; Kung, Victor W S; Hicks, Gareth A; Schemann, Michael; Barnes, Michael R; Kenakin, Terrence P; Granier, Sébastien; Sanger, Gareth J

Broad, John; Maurel, Damien; Kung, Victor W S; Hicks, Gareth A; Schemann, Michael; Barnes, Michael R; Kenakin, Terrence P; Granier, Sébastien; Sanger, Gareth J.

Affiliation

Broad J; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.
Maurel D; Institut de Génomique Fonctionnelle, Dépt de Pharmacologie Moléculaire, UMR 5203 CNRS-U 661 INSERM, Univ Montpellier I &II, 141, 34094 Montpellier, France.
Kung VW; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.
Hicks GA; Tioga Pharmaceuticals, 9393 Towne Centre Drive, Suite 200, San Diego, California, USA.
Schemann M; Human Biology, TU München, D-85350 Freising-Weihenstephan, Germany.
Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.
Kenakin TP; Dept of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Granier S; Institut de Génomique Fonctionnelle, Dépt de Pharmacologie Moléculaire, UMR 5203 CNRS-U 661 INSERM, Univ Montpellier I &II, 141, 34094 Montpellier, France.
Sanger GJ; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.

Sci Rep ; 6: 30797, 2016 08 05.

Article de En | MEDLINE | ID: mdl-27492592

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protéines recombinantes / Récepteur kappa / Muqueuse intestinale Type d'étude: Prognostic_studies / Risk_factors_studies Limites: Animals / Humans Langue: En Journal: Sci Rep Année: 2016 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Royaume-Uni

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