Anti-cancer effect of pristimerin by inhibition of HIF-1&#945; involves the SPHK-1 pathway in hypoxic prostate cancer cells.

Lee, Seon-Ok; Kim, Joo-Seok; Lee, Myoung-Sun; Lee, Hyo-Jeong

Anti-cancer effect of pristimerin by inhibition of HIF-1α involves the SPHK-1 pathway in hypoxic prostate cancer cells.

Lee, Seon-Ok; Kim, Joo-Seok; Lee, Myoung-Sun; Lee, Hyo-Jeong.

Affiliation

Lee SO; Department of Cancer Preventive Material Development, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Kim JS; College of Korean Medicine, Kyung Hee University, 1Hoegi-dong, Dongdaemun-gu, Seoul, 130-701, Republic of Korea.
Lee MS; College of Korean Medicine, Kyung Hee University, 1Hoegi-dong, Dongdaemun-gu, Seoul, 130-701, Republic of Korea.
Lee HJ; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, Republic of Korea.

BMC Cancer ; 16: 701, 2016 08 31.

Article de En | MEDLINE | ID: mdl-27581969

Sujet(s)
Mots clés

HIF-1α; Hypoxia; Pristimerin; Prostate cancer; SPHK-1

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs de la prostate / Triterpènes / Phosphotransferases (Alcohol Group Acceptor) / Sous-unité alpha du facteur-1 induit par l'hypoxie / Antinéoplasiques Limites: Humans / Male Langue: En Journal: BMC Cancer Sujet du journal: NEOPLASIAS Année: 2016 Type de document: Article Pays de publication: Royaume-Uni

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