Powering Tumor Metastasis with Recycled Fuel.

Hung, Mien-Chie; Yang, Riyao; Sun, Yutong

Hung, Mien-Chie; Yang, Riyao; Sun, Yutong.

Affiliation

Hung MC; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University, Taichung 404, Taiwan. Electronic address: mhung@mdanderson.org.
Yang R; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Sun Y; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Cancer Cell ; 30(3): 374-375, 2016 09 12.

Article de En | MEDLINE | ID: mdl-27622330

RÉSUMÉ

Receptor tyrosine kinase (RTK) recycling is of critical importance for RTK signaling and cancer, yet the process is poorly understood. In this issue, Ye et al. identify GOLM1 as a cargo adaptor that drives hepatocellular carcinoma metastasis by promoting EGFR recycling and provide insights into how this process is regulated.

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteurs à activité tyrosine kinase / Carcinome hépatocellulaire Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Cancer Cell Sujet du journal: NEOPLASIAS Année: 2016 Type de document: Article Pays de publication: États-Unis d'Amérique

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