A Randomized Study Evaluating Oral Fusidic Acid (CEM-102) in Combination With Oral Rifampin Compared With Standard-of-Care Antibiotics for Treatment of Prosthetic Joint Infections: A Newly Identified Drug-Drug Interaction.

Pushkin, Richard; Iglesias-Ussel, Maria D; Keedy, Kara; MacLauchlin, Chris; Mould, Diane R; Berkowitz, Richard; Kreuzer, Stephan; Darouiche, Rabih; Oldach, David; Fernandes, Prabha

Pushkin, Richard; Iglesias-Ussel, Maria D; Keedy, Kara; MacLauchlin, Chris; Mould, Diane R; Berkowitz, Richard; Kreuzer, Stephan; Darouiche, Rabih; Oldach, David; Fernandes, Prabha.

Affiliation

Pushkin R; Cempra Inc.
Iglesias-Ussel MD; Cempra Inc.
Keedy K; University of North Carolina, Chapel Hill.
MacLauchlin C; Cempra Inc.
Mould DR; Cempra Inc.
Berkowitz R; Projections Research Inc, Phoenixville, Pennsylvania.
Kreuzer S; Phoenix Clinical Research, Tamarac, Florida.
Darouiche R; Memorial Bone and Joint Clinic and University of Texas Health Science Center at Houston.
Oldach D; Departments of Medicine, Surgery, and Physical Medicine and Rehabilitation, Michael E. DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas.
Fernandes P; Cempra Inc.

Clin Infect Dis ; 63(12): 1599-1604, 2016 Dec 15.

Article de En | MEDLINE | ID: mdl-27682068

Sujet(s)
Mots clés

arthroplasty; fusidic acid; prosthetic joint infection; rifampin

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Collection: 01-internacional Base de données: MEDLINE Sujet principal: Rifampicine / Infections bactériennes / Infections dues aux prothèses / Acide fusidique / Antibactériens Type d'étude: Clinical_trials Limites: Aged / Aged80 / Female / Humans / Male / Middle aged Langue: En Journal: Clin Infect Dis Sujet du journal: DOENCAS TRANSMISSIVEIS Année: 2016 Type de document: Article Pays de publication: États-Unis d'Amérique

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