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Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation.
Phillips, Nick E; Manning, Cerys S; Pettini, Tom; Biga, Veronica; Marinopoulou, Elli; Stanley, Peter; Boyd, James; Bagnall, James; Paszek, Pawel; Spiller, David G; White, Michael Rh; Goodfellow, Marc; Galla, Tobias; Rattray, Magnus; Papalopulu, Nancy.
Affiliation
  • Phillips NE; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Manning CS; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Pettini T; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Biga V; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Marinopoulou E; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Stanley P; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Boyd J; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Bagnall J; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Paszek P; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Spiller DG; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • White MR; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
  • Goodfellow M; College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, United Kingdom.
  • Galla T; Centre for Biomedical Modelling and Analysis, University of Exeter, Exeter, United Kingdom.
  • Rattray M; EPSRC Centre for Predictive Modelling in Healthcare, University of Exeter, Exeter, United Kingdom.
  • Papalopulu N; Theoretical Physics, School of Physics and Astronomy, University of Manchester, Manchester, United Kingdom.
Elife ; 52016 10 04.
Article de En | MEDLINE | ID: mdl-27700985
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cellules souches / Différenciation cellulaire / Régulation de l'expression des gènes / MicroARN / Prolifération cellulaire / Facteur de transcription HES-1 / Neurones Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Elife Année: 2016 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Royaume-Uni
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cellules souches / Différenciation cellulaire / Régulation de l'expression des gènes / MicroARN / Prolifération cellulaire / Facteur de transcription HES-1 / Neurones Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Elife Année: 2016 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Royaume-Uni