Therapeutic relevance of mTOR inhibition in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism.

Vogel, K R; Ainslie, G R; Jansen, E E W; Salomons, G S; Gibson, K M

Vogel, K R; Ainslie, G R; Jansen, E E W; Salomons, G S; Gibson, K M.

Affiliation

Vogel KR; Division of Experimental and Systems Pharmacology, College of Pharmacy, Washington State University, Spokane, WA, USA.
Ainslie GR; Division of Experimental and Systems Pharmacology, College of Pharmacy, Washington State University, Spokane, WA, USA.
Jansen EE; Metabolic Unit, Department of Clinical Chemistry, VU University Medical Center, Neuroscience Campus, Amsterdam, The Netherlands.
Salomons GS; Metabolic Unit, Department of Clinical Chemistry, VU University Medical Center, Neuroscience Campus, Amsterdam, The Netherlands.
Gibson KM; Division of Experimental and Systems Pharmacology, College of Pharmacy, Washington State University, Spokane, WA, USA. Electronic address: mike.gibson@wsu.edu.

Biochim Biophys Acta Mol Basis Dis ; 1863(1): 33-42, 2017 01.

Article de En | MEDLINE | ID: mdl-27760377

Sujet(s)
Mots clés

GABA; Oxidative stress; Succinic semialdehyde dehydrogenase deficiency; Torin 1; Torin 2; mTOR

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Incapacités de développement / Délétion de gène / Succinate-semialdehyde dehydrogenase / Sérine-thréonine kinases TOR / Acide gamma-amino-butyrique / Aminoacidopathies congénitales Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: Biochim Biophys Acta Mol Basis Dis Année: 2017 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Pays-Bas

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google