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Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment.
Dong, Lei; Yu, Wen-Mei; Zheng, Hong; Loh, Mignon L; Bunting, Silvia T; Pauly, Melinda; Huang, Gang; Zhou, Muxiang; Broxmeyer, Hal E; Scadden, David T; Qu, Cheng-Kui.
Affiliation
  • Dong L; Department of Pediatrics, Division of Hematology/Oncology, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Yu WM; Department of Pediatrics, Division of Hematology/Oncology, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Zheng H; Department of Pediatrics, Division of Hematology/Oncology, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Loh ML; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of California at San Francisco, San Francisco, California 94122, USA.
  • Bunting ST; Department of Pathology, Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia 30322, USA.
  • Pauly M; Department of Pediatrics, Division of Hematology/Oncology, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Huang G; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital, University of Cincinnati, Cincinnati, Ohio 45229, USA.
  • Zhou M; Department of Pediatrics, Division of Hematology/Oncology, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Broxmeyer HE; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
  • Scadden DT; Center for Regenerative Medicine and MGH Cancer Center, Massachusetts General Hospital, Department of Stem Cell and Regenerative Biology and Harvard Stem Cell Institute, Harvard University, Boston, Massachusetts 02114, USA.
  • Qu CK; Department of Pediatrics, Division of Hematology/Oncology, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Nature ; 539(7628): 304-308, 2016 11 10.
Article de En | MEDLINE | ID: mdl-27783593
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cellules souches hématopoïétiques / Leucémies / Transformation cellulaire néoplasique / Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Niche de cellules souches / Microenvironnement cellulaire Limites: Animals / Female / Humans / Male Langue: En Journal: Nature Année: 2016 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cellules souches hématopoïétiques / Leucémies / Transformation cellulaire néoplasique / Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Niche de cellules souches / Microenvironnement cellulaire Limites: Animals / Female / Humans / Male Langue: En Journal: Nature Année: 2016 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni