Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus.

Leslie, George J; Wang, Jianbin; Richardson, Max W; Haggarty, Beth S; Hua, Kevin L; Duong, Jennifer; Secreto, Anthony J; Jordon, Andrea P O; Romano, Josephine; Kumar, Kritika E; DeClercq, Joshua J; Gregory, Philip D; June, Carl H; Root, Michael J; Riley, James L; Holmes, Michael C; Hoxie, James A

Leslie, George J; Wang, Jianbin; Richardson, Max W; Haggarty, Beth S; Hua, Kevin L; Duong, Jennifer; Secreto, Anthony J; Jordon, Andrea P O; Romano, Josephine; Kumar, Kritika E; DeClercq, Joshua J; Gregory, Philip D; June, Carl H; Root, Michael J; Riley, James L; Holmes, Michael C; Hoxie, James A.

Affiliation

Leslie GJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Wang J; Sangamo BioSciences Inc., Richmond, CA, United States of America.
Richardson MW; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Haggarty BS; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Hua KL; Sangamo BioSciences Inc., Richmond, CA, United States of America.
Duong J; Sangamo BioSciences Inc., Richmond, CA, United States of America.
Secreto AJ; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Jordon AP; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Romano J; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Kumar KE; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
DeClercq JJ; Sangamo BioSciences Inc., Richmond, CA, United States of America.
Gregory PD; Sangamo BioSciences Inc., Richmond, CA, United States of America.
June CH; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Root MJ; Department of Biochemistry and Molecular Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, United States of America.
Riley JL; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Holmes MC; Sangamo BioSciences Inc., Richmond, CA, United States of America.
Hoxie JA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.

PLoS Pathog ; 12(11): e1005983, 2016 Nov.

Article de En | MEDLINE | ID: mdl-27855210

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Fragments peptidiques / Lymphocytes T CD4/ / Protéine d'enveloppe gp41 du VIH / Infections à VIH / VIH-1 (Virus de l'Immunodéficience Humaine de type 1) / Récepteurs CXCR4 / Pénétration virale Limites: Animals / Humans Langue: En Journal: PLoS Pathog Année: 2016 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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