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Mobilization of hematopoietic stem cells with the novel CXCR4 antagonist POL6326 (balixafortide) in healthy volunteers-results of a dose escalation trial.
Karpova, Darja; Bräuninger, Susanne; Wiercinska, Eliza; Krämer, Ariane; Stock, Belinda; Graff, Jochen; Martin, Hans; Wach, Achim; Escot, Christophe; Douglas, Garry; Romagnoli, Barbara; Chevalier, Eric; Dembowski, Klaus; Hooftman, Leon; Bonig, Halvard.
Affiliation
  • Karpova D; German Red Cross Blood Service BaWüHe, Institute Frankfurt, Frankfurt, Germany.
  • Bräuninger S; Department of Internal Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University Medical School, St. Louis, MO, USA.
  • Wiercinska E; German Red Cross Blood Service BaWüHe, Institute Frankfurt, Frankfurt, Germany.
  • Krämer A; German Red Cross Blood Service BaWüHe, Institute Frankfurt, Frankfurt, Germany.
  • Stock B; German Red Cross Blood Service BaWüHe, Institute Frankfurt, Frankfurt, Germany.
  • Graff J; German Red Cross Blood Service BaWüHe, Institute Frankfurt, Frankfurt, Germany.
  • Martin H; Clinical Trial Center Rhein-Main (KSRM), Pharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe University, Frankfurt, Germany.
  • Wach A; Department of Medicine II, Goethe University, Frankfurt, Germany.
  • Escot C; Polyphor Ltd, Allschwil, Switzerland.
  • Douglas G; Polyphor Ltd, Allschwil, Switzerland.
  • Romagnoli B; Polyphor Ltd, Allschwil, Switzerland.
  • Chevalier E; Polyphor Ltd, Allschwil, Switzerland.
  • Dembowski K; Polyphor Ltd, Allschwil, Switzerland.
  • Hooftman L; Polyphor Ltd, Allschwil, Switzerland.
  • Bonig H; Polyphor Ltd, Allschwil, Switzerland.
J Transl Med ; 15(1): 2, 2017 01 03.
Article de En | MEDLINE | ID: mdl-28049490

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Peptides / Peptides cycliques / Récepteurs CXCR4 / Mobilisation de cellules souches hématopoïétiques / Volontaires sains Type d'étude: Prognostic_studies Limites: Humans / Male Langue: En Journal: J Transl Med Année: 2017 Type de document: Article Pays d'affiliation: Allemagne

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Peptides / Peptides cycliques / Récepteurs CXCR4 / Mobilisation de cellules souches hématopoïétiques / Volontaires sains Type d'étude: Prognostic_studies Limites: Humans / Male Langue: En Journal: J Transl Med Année: 2017 Type de document: Article Pays d'affiliation: Allemagne