6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17ß-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation.

Benek, Ondrej; Hroch, Lukas; Aitken, Laura; Dolezal, Rafael; Guest, Patrick; Benkova, Marketa; Soukup, Ondrej; Musil, Karel; Kuca, Kamil; Smith, Terry K; Gunn-Moore, Frank; Musilek, Kamil

Benek, Ondrej; Hroch, Lukas; Aitken, Laura; Dolezal, Rafael; Guest, Patrick; Benkova, Marketa; Soukup, Ondrej; Musil, Karel; Kuca, Kamil; Smith, Terry K; Gunn-Moore, Frank; Musilek, Kamil.

Affiliation

Gunn-Moore F; University of St. Andrews, School of Biology, Medical and Biological Sciences Building, North Haugh, St. Andrews KY16 9TF, United Kingdom.
Musilek K; University Hospital in Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.

Med Chem ; 2017 Jan 09.

Article de En | MEDLINE | ID: mdl-28067167

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Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Med Chem Sujet du journal: QUIMICA Année: 2017 Type de document: Article

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Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Med Chem Sujet du journal: QUIMICA Année: 2017 Type de document: Article