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A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.
Haddick, Patrick C G; Larson, Jessica L; Rathore, Nisha; Bhangale, Tushar R; Phung, Qui T; Srinivasan, Karpagam; Hansen, David V; Lill, Jennie R; Pericak-Vance, Margaret A; Haines, Jonathan; Farrer, Lindsay A; Kauwe, John S; Schellenberg, Gerard D; Cruchaga, Carlos; Goate, Alison M; Behrens, Timothy W; Watts, Ryan J; Graham, Robert R; Kaminker, Joshua S; van der Brug, Marcel.
Affiliation
  • Haddick PC; Department of Diagnostic Discovery, Genentech Inc., South San Francisco, CA, USA.
  • Larson JL; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA, USA.
  • Rathore N; Department of Human Genetics, Genentech Inc., South San Francisco, CA, USA.
  • Bhangale TR; Department of Human Genetics, Genentech Inc., South San Francisco, CA, USA.
  • Phung QT; Department of Protein Chemistry, Genentech Inc., South San Francisco, CA, USA.
  • Srinivasan K; Department of Neuroscience, Genentech Inc., South San Francisco, CA, USA.
  • Hansen DV; Department of Neuroscience, Genentech Inc., South San Francisco, CA, USA.
  • Lill JR; Department of Protein Chemistry, Genentech Inc., South San Francisco, CA, USA.
  • Pericak-Vance MA; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.
  • Haines J; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, FL, USA.
  • Farrer LA; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.
  • Kauwe JS; Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine and Public Health, Boston, MA, USA.
  • Schellenberg GD; Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, MA, USA.
  • Cruchaga C; Department of Ophthalmology, Boston University Schools of Medicine and Public Health, Boston, MA, USA.
  • Goate AM; Department of Epidemiology, Boston University Schools of Medicine and Public Health, Boston, MA, USA.
  • Behrens TW; Department of Biostatistics, Boston University Schools of Medicine and Public Health, Boston, MA, USA.
  • Watts RJ; Department of Biology, Brigham Young University, Provo, UT, USA.
  • Graham RR; Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
  • Kaminker JS; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
  • van der Brug M; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.
J Alzheimers Dis ; 56(3): 1037-1054, 2017.
Article de En | MEDLINE | ID: mdl-28106546
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Encéphale / Récepteurs à l'interleukine-6 / Polymorphisme de nucléotide simple / Maladie d'Alzheimer Type d'étude: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limites: Aged / Aged80 / Animals / Female / Humans / Male Langue: En Journal: J Alzheimers Dis Sujet du journal: GERIATRIA / NEUROLOGIA Année: 2017 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Pays-Bas
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Encéphale / Récepteurs à l'interleukine-6 / Polymorphisme de nucléotide simple / Maladie d'Alzheimer Type d'étude: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limites: Aged / Aged80 / Animals / Female / Humans / Male Langue: En Journal: J Alzheimers Dis Sujet du journal: GERIATRIA / NEUROLOGIA Année: 2017 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Pays-Bas