Synthesis and Biotransformation of Bicyclic Unsaturated Lactones with Three or Four Methyl Groups.
Molecules
; 22(1)2017 Jan 17.
Article
de En
| MEDLINE
| ID: mdl-28106750
ABSTRACT
The aim of this study was to obtain new unsaturated lactones by chemical synthesis and their microbial transformations using fungal strains. Some of these strains were able to transform unsaturated lactones into different hydroxy or epoxy derivatives. Strains of Syncephalastrum racemosum and Absidia cylindrospora gave products with a hydroxy group introduced into a tertiary carbon, while the Penicillium vermiculatum strain hydroxylated primary carbons. The Syncephalastrum racemosum strain hydroxylated both substrates in an allylic position. Using the Absidia cylindrospora and Penicillium vermiculatum strains led to the obtained epoxylactones. The structures of all lactones were established on the basis of spectroscopic data.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Biotransformation
/
Lactones
Langue:
En
Journal:
Molecules
Sujet du journal:
BIOLOGIA
Année:
2017
Type de document:
Article
Pays d'affiliation:
Pologne