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Efficient Preparation of Site-Specific Antibody-Drug Conjugates Using Cysteine Insertion.
Dimasi, Nazzareno; Fleming, Ryan; Zhong, Haihong; Bezabeh, Binyam; Kinneer, Krista; Christie, Ronald J; Fazenbaker, Christine; Wu, Herren; Gao, Changshou.
Affiliation
  • Dimasi N; Antibody Discovery and Protein Engineering and ‡Oncology Research, MedImmune , Gaithersburg, Maryland 20878, United States.
  • Fleming R; Antibody Discovery and Protein Engineering and ‡Oncology Research, MedImmune , Gaithersburg, Maryland 20878, United States.
  • Zhong H; Antibody Discovery and Protein Engineering and ‡Oncology Research, MedImmune , Gaithersburg, Maryland 20878, United States.
  • Bezabeh B; Antibody Discovery and Protein Engineering and ‡Oncology Research, MedImmune , Gaithersburg, Maryland 20878, United States.
  • Kinneer K; Antibody Discovery and Protein Engineering and ‡Oncology Research, MedImmune , Gaithersburg, Maryland 20878, United States.
  • Christie RJ; Antibody Discovery and Protein Engineering and ‡Oncology Research, MedImmune , Gaithersburg, Maryland 20878, United States.
  • Fazenbaker C; Antibody Discovery and Protein Engineering and ‡Oncology Research, MedImmune , Gaithersburg, Maryland 20878, United States.
  • Wu H; Antibody Discovery and Protein Engineering and ‡Oncology Research, MedImmune , Gaithersburg, Maryland 20878, United States.
  • Gao C; Antibody Discovery and Protein Engineering and ‡Oncology Research, MedImmune , Gaithersburg, Maryland 20878, United States.
Mol Pharm ; 14(5): 1501-1516, 2017 05 01.
Article de En | MEDLINE | ID: mdl-28245132
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cystéine / Anticorps monoclonaux / Antinéoplasiques Limites: Animals / Female / Humans Langue: En Journal: Mol Pharm Sujet du journal: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Année: 2017 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cystéine / Anticorps monoclonaux / Antinéoplasiques Limites: Animals / Female / Humans Langue: En Journal: Mol Pharm Sujet du journal: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Année: 2017 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique