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Topiramate modulates post-infarction inflammation primarily by targeting monocytes or macrophages.
Wang, Zhaohui; Huang, Shiyuan; Sheng, Yuling; Peng, Xu; Liu, Hui; Jin, Nan; Cai, Jun; Shu, Yanwen; Li, Ting; Li, Ping; Fan, Cheng; Hu, Xiaofan; Zhang, Wenyong; Long, Rui; You, Ya; Huang, Caihong; Song, Yi; Xiang, Chunhua; Wang, Jue; Yang, Yong; Liu, Kun.
Affiliation
  • Wang Z; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Huang S; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Sheng Y; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Peng X; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Liu H; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Jin N; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Cai J; Department of Emergency Surgery, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Ave, Wuhan 430014, China.
  • Shu Y; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Li T; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Li P; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Fan C; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Hu X; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Zhang W; Department of Geriatrics, LIYUAN Hospital, Tongji Medical College, Huazhong University of Science and Technology, 39 Yanhu Ave, Wuhan 430077, China.
  • Long R; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • You Y; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Huang C; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Song Y; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Xiang C; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Wang J; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
  • Yang Y; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
  • Liu K; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan 430022, China.
Cardiovasc Res ; 113(5): 475-487, 2017 Apr 01.
Article de En | MEDLINE | ID: mdl-28339742
Sujet(s)
Anti-inflammatoires/pharmacologie; Fructose/analogues et dérivés; Agonistes GABA/pharmacologie; Ventricules cardiaques/effets des médicaments et des substances chimiques; Macrophages/effets des médicaments et des substances chimiques; Monocytes/effets des médicaments et des substances chimiques; Infarctus du myocarde/traitement médicamenteux; Myocardite/prévention et contrôle; Récepteurs GABA/effets des médicaments et des substances chimiques; Animaux; Antigènes Ly/métabolisme; Collagène/métabolisme; Modèles animaux de maladie humaine; Fibrose; Fructose/pharmacologie; Rupture du coeur post-infarctus/métabolisme; Rupture du coeur post-infarctus/physiopathologie; Rupture du coeur post-infarctus/prévention et contrôle; Ventricules cardiaques/métabolisme; Ventricules cardiaques/anatomopathologie; Ventricules cardiaques/physiopathologie; Macrophages/métabolisme; Souris de lignée C57BL; Monocytes/métabolisme; Infarctus du myocarde/métabolisme; Infarctus du myocarde/anatomopathologie; Infarctus du myocarde/physiopathologie; Myocardite/métabolisme; Myocardite/anatomopathologie; Myocardite/physiopathologie; Myocarde/métabolisme; Myocarde/anatomopathologie; Phénotype; Récepteurs GABA/métabolisme; Récepteurs GABA-A/effets des médicaments et des substances chimiques; Récepteurs GABA-A/métabolisme; Facteurs temps; Topiramate; Dysfonction ventriculaire gauche/métabolisme; Dysfonction ventriculaire gauche/physiopathologie; Dysfonction ventriculaire gauche/prévention et contrôle; Fonction ventriculaire gauche/effets des médicaments et des substances chimiques; Remodelage ventriculaire/effets des médicaments et des substances chimiques
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Monocytes / Récepteurs GABA / Agonistes GABA / Fructose / Ventricules cardiaques / Macrophages / Anti-inflammatoires / Infarctus du myocarde / Myocardite Type d'étude: Prognostic_studies Langue: En Journal: Cardiovasc Res Année: 2017 Type de document: Article Pays d'affiliation: Chine
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Monocytes / Récepteurs GABA / Agonistes GABA / Fructose / Ventricules cardiaques / Macrophages / Anti-inflammatoires / Infarctus du myocarde / Myocardite Type d'étude: Prognostic_studies Langue: En Journal: Cardiovasc Res Année: 2017 Type de document: Article Pays d'affiliation: Chine