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Synthesis and antiproteasomal activity of novel O-benzyl salicylamide-based inhibitors built from leucine and phenylalanine.
Jorda, Radek; Dusek, Jan; Reznícková, Eva; Pauk, Karel; Magar, Pratibha P; Imramovský, Ales; Krystof, Vladimír.
Affiliation
  • Jorda R; Laboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University & Institute of Experimental Botany ASCR, Slechtitelu 27, 78371 Olomouc, Czech Republic.
  • Dusek J; Institute of Organic Chemistry and Technology, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic.
  • Reznícková E; Laboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University & Institute of Experimental Botany ASCR, Slechtitelu 27, 78371 Olomouc, Czech Republic.
  • Pauk K; Institute of Organic Chemistry and Technology, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic.
  • Magar PP; Institute of Organic Chemistry and Technology, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic.
  • Imramovský A; Institute of Organic Chemistry and Technology, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic. Electronic address: Ales.Imramovsky@upce.cz.
  • Krystof V; Laboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University & Institute of Experimental Botany ASCR, Slechtitelu 27, 78371 Olomouc, Czech Republic. Electronic address: vladimir.krystof@upol.cz.
Eur J Med Chem ; 135: 142-158, 2017 Jul 28.
Article de En | MEDLINE | ID: mdl-28441582

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Phénylalanine / Salicylamides / Proteasome endopeptidase complex / Inhibiteurs du protéasome / Leucine / Antinéoplasiques Limites: Humans Langue: En Journal: Eur J Med Chem Année: 2017 Type de document: Article Pays d'affiliation: République tchèque Pays de publication: France

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Phénylalanine / Salicylamides / Proteasome endopeptidase complex / Inhibiteurs du protéasome / Leucine / Antinéoplasiques Limites: Humans Langue: En Journal: Eur J Med Chem Année: 2017 Type de document: Article Pays d'affiliation: République tchèque Pays de publication: France