Ventricular Energetics in Pediatric Left Ventricular Assist Device Patients: A Retrospective Clinical Study.
ASAIO J
; 63(6): 815-823, 2017.
Article
de En
| MEDLINE
| ID: mdl-28514263
ABSTRACT
The aim of this study is to estimate the trend of right and left energetic parameters in left ventricular assist device (LVAD) pediatric patients. Echocardiographic data were retrospectively collected at the baseline, in the acute phase after and at the monthly follow-ups till the LVAD explantation to estimate left and right ventricular energetic parameters. A significant relationship between the left and right ventricular energetic parameter trends was found along all the study period. Left ventricular end-systolic pressure-volume relationship improved till the follow-up of 2 months and then progressively decreases. Left arteroventricular coupling decreases after the LVAD, and right arteroventricular coupling decreases at the short-term follow-up. Left ventricular external work, potential energy, and pressure-volume area decrease at the short-term follow-up and then increase progressively. Right ventricular external work, potential energy, and pressure-volume area increase after the LVAD implantation. Left (right) cardiac mechanical efficiency is improved (worsened) by the LVAD. Energetic variables show that the LVAD benefits could decrease over time. A continuous and patient tailored LVAD setting could contribute to prolong LVAD benefits. The introduction of energetic parameters could lead to a more complete evaluation of LVAD patients' outcome which is a multiparametric process.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Dispositifs d'assistance circulatoire
/
Ventricules cardiaques
Type d'étude:
Observational_studies
Limites:
Child
/
Female
/
Humans
/
Infant
/
Male
Langue:
En
Journal:
ASAIO J
Sujet du journal:
TRANSPLANTE
Année:
2017
Type de document:
Article
Pays d'affiliation:
Italie