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Antidiabetic Compounds in Syzygium cumini Decoction and Ready to Serve Herbal Drink.
Perera, P R D; Ekanayake, S; Ranaweera, K K D S.
Affiliation
  • Perera PRD; Department of Food Science and Technology, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
  • Ekanayake S; Department of Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
  • Ranaweera KKDS; Department of Food Science and Technology, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Article de En | MEDLINE | ID: mdl-28572825
ABSTRACT
Herbal beverages with desirable sensory attributes are an ideal way to offer consumers with phytochemicals having specific health promoting functionalities. Syzygium cumini bark decoction is used in treating diabetes mellitus in Ayurveda medicine. This work attempted to prove the presence of antidiabetic compounds in the S. cumini decoction and the ready to serve (RTS) herbal drink developed using the decoction. Activity guided fractionation of the decoction of the S. cumini was carried out by sequential extraction with organic solvents of different polarities. Thin Layer Chromatography (TLC) with authentic compounds and HPLC were performed for identification and confirmation of the compounds in the decoction and the RTS herbal drink. Presence of gallic and ellagic acids in the decoction and RTS herbal drink was proven and confirmed with HPLC. The LC UV-VIS spectra of the two compounds were identical with the corresponding spectra of the library. Further, gallic acid and umbelliferone were determined as the active compounds in the decoction by TLC and were confirmed by cochromatography with authentic compounds. The present investigation confirmed the presence of gallic acid, ellagic acid, and umbelliferone which are proven to have antidiabetic activities in the decoction and the RTS herbal drink prepared with the decoction.

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Evid Based Complement Alternat Med Année: 2017 Type de document: Article Pays d'affiliation: Sri Lanka

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Evid Based Complement Alternat Med Année: 2017 Type de document: Article Pays d'affiliation: Sri Lanka